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The person can't sense the earth is a round ball. All the houses and bridges are designed in a straight line. For the living circumstance, the world is flat. I calculate if someone on lowest cloud, the horizon the person can see is about 117km (70 miles) away. So the area is between 30km^2 to 40 km^2. The size of Michigan State is five times of that area. Well of course, in the US, everyone behaves like an independent person and know the size of their state(estate). At least,

Qi Lu, WIX-AI I am thinking about if I can use retina as a neural network to study depression. The following paragraph are generated through AI with some added knowledge from my research. The mammal eye is never truly “off.” Even in complete darkness, photoreceptors keep a steady electrical flow running. That flow, called the dark current, helps rods and cones stay ready for the next photon of light. It is one of the quiet background processes that makes vision possible. This

I am doing multichannel recording of retina from blind mice. Before recording the retina is transfected with CO3M in bipolar cells. So, the bipolar cells are the light sensor to give visual signal to ganglion cells. To achieve this purpose, checkbox or pictures are projected to the whole retina (20 mm2).

The pain of heartbreak is similar to phantom limb pain. Because the central nervous system and peripheral nervous system are connected, they converse with each other, and they mutually release substances to maintain their connection with one another; the absence of that directly results in pain. If the intimate relationship between people no longer receives a response from one side, and the expecting party doesn't receive the anticipated sounds, touches, texts—these substance

LU, Qi's Ph.D. mentor is Dr. PAN, Zhuo-Hua. Dr. Pan is one of the pioneers on the field of Optogenetics. Especially, he is the first scientist propose the idea of restoration of vision with optogenetic approach. The field of neuroscience is evolving rapidly, and at the forefront of this evolution is the qluLab team. The qlulab's ongoing project in neuron remodeling research is not just advancing our understanding of the neural network but also opening new avenues for treati

Vision loss affects millions of people worldwide, often leading to a diminished quality of life. Traditional treatments for eye diseases have limitations, and many patients are left with few options. However, recent advancements in optogenetic gene therapy are opening new doors for vision restoration. This innovative approach combines genetics and light to restore sight, offering hope to those with degenerative eye conditions. In this post, we will explore the science behind

Dose curve of Co3M based on behavioral outcome of optomotor response. The injection viral dose of  1.5 × 108 vg/eye start to reach the behavioral result plateau. LU, Q., WRIGHT, A. & PAN, Z. H. 2024. AAV dose-dependent transduction efficiency in retinal ganglion cells and functional efficacy of optogenetic vision restoration. Gene Ther. DOI: 10.1038/s41434-024-00485-7 Accession Number: 39237697 Abstract Optogenetics is a promising approach for restoring vision to the blind af